1 BP-VLP Technology
Nanovax Co., Ltd is developing a next-generation vaccine platform using Virus-Like Particle (VLP) technology derived from bacteriophages (BP).
The BP-VLP platform offers superior safety and efficiency compared to conventional vaccines. It also enables the presentation of diverse antigens, making it an optimized solution for the prevention and treatment of infectious diseases.
Advantages of Bacterial host.
High expression level in E.coli
High solubilized antigen
Simple single coat protein.
Convenient Multiple Antigen Present.
Stable VLP formation
Non-pathogenic to mammalian host
BP-VLP
2 Key Advantages of BP-VLP Technology
Stable Bacteriophage-Based Expression System - Enables large-scale expression and production using bacterial hosts
High Antigen Expression in E. coli - Enhances productivity and cost-efficiency in vaccine development
Highly Solubilized Antigen - Minimizes protein aggregation and optimizes immune response
Simple Single Coat Protein Structure - Forms stable VLPs without complex assembly processes
Convenient Multiple Antigen Presentation - Capable of targeting multiple pathogens simultaneously
Stable VLP Formation - Maintains vaccine efficacy and supports long-term storage
Non-Pathogenic to Mammalian Hosts - Provides a safe platform for human and animal applications
BP-VLP
Antigen
Antigen-VLP conjugate
Applications of BP-VLP Technology
3 Application Areas of BP-VLP Technology
Development of Immune Adjuvants that Stimulate T-cell/B-cell Responses
Vaccine Development Using Immunogenic Epitopes/Subunit Antigens
Development of Targeted Delivery Systems for Specific Antigens
Application Areas of Nanovax’s BP-VLP Technology
Nanovax Co., Ltd is developing a next-generation vaccine platform using Virus-Like Particle (VLP) technology derived from bacteriophages (BP).
The BP-VLP platform offers superior safety and efficiency compared to conventional vaccines. It also enables the presentation of diverse antigens, making it an optimized solution for the prevention and treatment of infectious diseases.
BP-VLP-Based Immune Adjuvant Development and Commercialization Plan
1 What is Ferritin?
A protein that stores and releases iron (Fe), an essential trace mineral in the body.
Forms stable nanoparticles through self-assembly.
Using recombinant technology, it is possible to fuse various antigens, compounds, etc., onto the particle surface, enabling applications in vaccine, drug delivery, and immune enhancer development.
2 Nanovax’s Ferritin-Based System
Nanovax Co., Ltd. is developing a next-generation biotechnology platform using ferritin's self-assembly properties for applications in vaccines, immune adjuvants, and drug delivery
Adjuvant
Drug Delivery System
Fenobody Platform
Vaccine